Common Bacterial Pathogen Antimicrobial Therapy
16 50 yo N meningitis, S pneumonia, H influ (nonimmunized pts) Vanc plus 3rd gen ceph
> 50 yo S pneumonia, N meningitis, L monocytogenes, aerobic gram-negative bacilli Vanc plus 3rd gen ceph and ampicillin
Immunocompromised L monocytogenes, aerobic gram-negative bacilli, S pneumonia, N meningitis Vanc plus 3rd gen ceph and ampicillin
Neurosurgery, head trauma, cerebrospinal trauma Staphylococci, aerobic gram-negative bacilli, S pneumonia Vanc plus either 3rd gen ceph with anti-pseudomonal coverage or meropenem
From Emergency Medicine Practice september 2009, Vol 11, No 9

 

Antibiotic
Dose Max dose Interval
Ceftriaxone 50 mg/kg 2 gm q 12 h
Vancomycin 15 mg/kg 500 mg q 6 h
Ampicillin 50 mg/kg 3 gm q 6 h
Cefepime 50 mg/kg 2 gm q 8 h
Ceftazidime 50 mg/kg 2 gm q 8 h
Cefotaxime 200 mg/kg/day    
Meropenem 40 mg/kg 2 gm q 8 h
Dexamethasone   10 mg q 6 h