Allowable combo’s of
FiO2 and PEEP (cm H2O)
FiO2 PEEP
0.3 5
0.4 5
0.4 8
0.5 8
0.5 10
0.6 10
0.7 10
0.7 12
0.7 14
0.8 14
0.9 14
0.9 16
0.9 18
1 18
1 20
1 22
1 24
 
Parameter Value Notes
Mode Volume AC  
Initial TV 6 mL/kg of predicted body weight
Pplat ≤ 30 cm H2O
RR 6-35 Needed to achieve pH 7.3-7.45
I:e 1:1 to 1:3  
Oxygenation goal PaO2 55-80 mm Hg
or
SaO2 88-95%
 
Weaning by PS when FiO2 ≤ 0.4

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